But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. Read more Anxiety over potential eye problems with Hydroxychloroquine is completely unwarranted if the dose is kept below 6mg/kg (2.2lbs) of body weight. Read more See 1 more doctor answer It can cause eye problems so you need to see an ophthalmologist and peridoic screenings. Read more Results are very good, particulary when used alone and better with methotrexate. Plaquenil missed dose Hydroxychloroquine adv Substitutes and alternatives to Plaquenil hydroxychloroquine for uses like Rheumatoid arthritis, Lupus and Malaria Other than medicine, additional lupus treatments include Surgery and transplants. In severe cases, lupus can cause damage to the organs -- especially the kidneys. C-Quinicrin is an alternative to Plaquenil that worked REALLY well for me. The last I heard it was no longer in the US, so I have been been without it and feel miserable. Has anyone found a way to buy it in Canada or elsewhere. Chloroquine can be substituted for Plaquenil but only in limited circumstances. Please provide more detailed information if you want a more specific answer. Read more See 1 more doctor answer Depends on what you are being treated for.... Read more While plaquenyl is a slow acting but effective drug, Prednisone is used in much higher doses in active sle. Arthritis (non-deforming) or arthralgias associated with the disease will have substantial pain relief with a dose this low. It's infusion intervals are longer, because the turnover of recptors is slower than the production of tnf-a itself. So other meds like Imuran and Cell Cept (mycophenolate mofetil) also reduce flares, but also increases infection. Read more It depends why you are taking Plaquenil in the first place. Apart from some stomach quiziies, I have never stopped this drug, as long as it demonstrated it is working. Other than that we see a few people who have increased skin pigmentation called "plaquenil ochronosis". The dirrence with Remicade (infliximab) is that it blocks the tnf-a receptor, rather than binding tnf-a itself, but it accomplishes the same thing. Lupus alternatives to plaquenil I am so afraid to take plaquenil for lupus treatment! any., Lupus Medications and Treatments Chloroquine phosphate and psoriasisChloroquine drug infoCan plaquenil cause liver problemsPlaquenil eye check Hello! Here is a short list Prednisone, Imuran, Remicade, Methotrexate Later sidesteps Prednisone's side effects, which include weight gain, mood swings, diabetes and eye problems, such as cataracts. I hope this was helpful enough. Alternatives to plaquenil Anti-Inflammatories.. Has anyone been on C-Quinicrin? It is an alternative to.. Plaquenil substitute - Things You Didn’t Know. I originally took Plaquenil Sanofi but this brand is now discontinued. The generic form of this, on my prescription, gives me serious digestion and stomach upsets to a point I spent months trying to figure out what I thought was irritable bowel syndrome. Has anyone found a good alternative UK brand that doesn't create this side affect. Plaquenil is used to treat fatigue, pain, skin rashes, and inflammation, especially around the lungs. It is one of the most frequently used medications for lupus because studies show that it may prevent lupus flares and kidney damage. Many lupus patients will stay on Plaquenil for many years and perhaps indefinitely. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis.