Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine dosage regimen Chloroquine cardiomyopathy beyond ocular adverse effects Can you od on plaquenil One of the potential long-term side-effects of using anti-malarial medications such as hydroxychloroquine Plaquenil, chloroquine, and quinacrine is the development of dark-colored patches on the skin. They often appear brown, black, or black and blue and tend to develop on the legs, especially around the shins. Hydroxychloroquine-Induced Hyperpigmentation. From the Departments of *Rheumatology and †Dermatology, Walter Reed National Military Medical Center; and ‡Uniformed Services University of the Health Sciences, Bethesda, MD. No financial support was received for this study. The authors declare no conflict of interest. Skin Hyperpigmentation with Hydroxychloroquine Hydroxychloroquine Plaquenil is a common trade name is an anti-inflammatory oral medication that is commonly used to treat many autoimmune diseases. In the hair clinic, we use it for diseases such as lichen planopilaris, frontal fibrosing alopecia, pseudopelade and discoid lupus. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil hydroxychloroquine hyperpigmentation Common and Rare Side Effects for Plaquenil Oral, Hydroxychloroquine-Induced Hyperpigmentation JCR Journal. Ashwagandha and plaquenilMolecular weight of chloroquine phosphateHydroxychloroquine in g6pd deficiencyDoes plaquenil lower sed rate Plaquenil and Skin hyperpigmentation - from FDA reports Summary Skin hyperpigmentation is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Omniscan, and have Arteriogram. Will you have Skin hyperpigmentation with Plaquenil.. Skin Pigmentation with Hydroxychloroquine Plaquenil.. Skin Discoloration and Plaquenil - Arthritis Information. Drug-Induced Hyperpigmentation caused by Plaquenil Hydroxychloroquine Plaquenil Hydroxycholoroquine Side Effects. Dermatologic side effects have included mucocutaneous hyperpigmentation, nonlight-sensitive psoriasis, bleaching of hair, alopecia, pruritus, photosensitivity, and skin eruptions such as urticarial, morbilliform, lichenoid, maculopapular, purpuric, erythema annulare centrifugum, Stevens-Johnson syndrome, acute generalized exanthematous pustulosis, and exfoliative dermatitis. Oct 30, 2008 Rare, previous reports of hyperpigmentation indicate the presence of both melanin and hemosiderin in patients being treated with antimalarial medication. To our knowledge, this staining pattern for hydroxychloroquine has not been previously reported in the literature and supports that hydroxychloroquine, in addition to chloroquine, binds to. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more.