Is tamoxifen an aromatase inhibitor

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    Is tamoxifen an aromatase inhibitor

    Aromatase inhibitors are a class of medicines that work by blocking the enzyme aromatase, the enzyme that converts androgens into estrogen. Aromatase inhibitors are used in the treatment of breast cancer to reduce levels of circulating estrogen. This means that less estrogen is available to stimulate the growth of estrogen receptor (ER) positive breast cancer cells, slowing or inhibiting the progression of these cancers. Approximately 80% of all breast cancers are ER positive. Aromatase inhibitors are unable to prevent the ovaries from making estrogen, which means that they are only used to treat breast cancer in postmenopausal women. There are three aromatase inhibitors: anastrozole, exemestane, and letrozole. By clicking Subscribe, I agree to the Terms & Conditions and Privacy Policy and understand that I may opt out of subscriptions at any time. uses cookies to improve performance by remembering your session ID when you navigate from page to page. Please set your browser to accept cookies to continue. This cookie stores just a session ID; no other information is captured. Accepting the NEJM cookie is necessary to use the website.

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    Jul 26, 2015. A study finds a class of hormonal drugs - aromatase inhibitors - are more effective than tamoxifen for reducing mortality among women with. Current data indicate that aromatase inhibitors are equivalent or superior to tamoxifen as first-line therapy for metastatic breast cancer and as neoadjuvant. Tamoxifen blocks the effects of estrogen in the breast but, oddly enough, acts like estrogen in other parts of the body. Aromatase inhibitors, however, knock out the.

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    Is tamoxifen an aromatase inhibitor

    When Are Aromatase Inhibitors Wrong for Breast Cancer? - Medscape, Aromatase Inhibitors in Breast Cancer An Overview - The Oncologist

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  5. BackgroundTreatment with an aromatase inhibitor for 5 years as up-front monotherapy or after tamoxifen therapy is the treatment of choice for hormone.

    • Extending Aromatase-Inhibitor Adjuvant Therapy to 10 Years -..
    • Tamoxifen vs Aromatase Inhibitors as Adjuvant Therapy - Health..
    • Hormone Therapy Dr Susan Love Foundation.

    Aromatase inhibitors. Although tamoxifen. Ovarian stimulation with the aromatase inhibitor letrozole has been proposed as one of the treatments for unexplained. Tamoxifen, previously known as. 4-OH-A was renamed to formestane and became the first “selective” aromatase inhibitor used clinically for the. Aromatase inhibitors are a type of hormone therapy used to treat breast. may be given an aromatase inhibitor, although another drug called tamoxifen is more.

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