I have been getting these horrible rashes and they are not related to sun exposure. I am starting to wonder if they are related to Plaquenil. Hydroxychloroquine and skin darkening Plaquenil and prednisone together I hope the itching has stopped by now. Hydroxychloroquine has an extremely long half life of around 32 days. This means that every 32 days, half of the previous amount of hydroxychloroquine in the body disappears. It takes around 5.5 half lives for a drug to be completely eliminated from your body meaning that you may need to wait for around. Drug-induced itch is defined as generalized itching without skin lesions, caused by a drug. Itching associated with drug-induced cholestasis is among the common dermatologic adverse events dAEs that induce itching. Some drugs such as opioids, antimalarials, and hydroxyethyl starch are known to induce itching without skin lesions. Mar 13, 2018 Shingles causes a painful rash, itching, and burning skin, and lasts for 3 to 5 weeks in most cases. People usually only experience shingles once, but the infection can recur. I've always been one to go for the natural route and am starting to feel like I should just stop taking everything and see what happens - so frustrating. My doctor now wants me to start on Chloroquine instead of plaquenil. How long does chloroquine itching last Chloroquine MedlinePlus Drug Information, Drug-Induced Itch Management. Chloroquine diphosphate storage Do not take more or less of it or take it more often than prescribed by your doctor. If you are taking hydroxychloroquine for symptoms of rheumatoid arthritis, your symptoms should improve within 6 months. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Hydroxychloroquine MedlinePlus Drug Information. How long does shingles last? Timeline and treatment. Medicines for the Prevention of Malaria While Traveling.. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat. I didn't get a rash from Plaq but I did itch like mad for a while. I know this is very frustrating but don't give up and I certainly don't stop taking your meds without talking to your doctor. It sometimes takes a while to find the right combo of meds but I do hope the Chloroquine will work better for you. Take care and keep us updated.