Part of that is due to less exercise, part due to having no appetite thus feeling like anything I can get down is ok. Well, now I've been exercising at almost my pre-Lupus rate (ran a marathon a year before), eating a more moderate diet (clean protein, vegs & fruits), and am no longer taking that weight & bloat causing Prednisone (off Pred almost 2 yrs now). My question: Do you feel like you've gained weight on Plaquenil (ie without Prednisone)? Hydroxychloroquine sun allergy What class of drug is hydroxychloroquine sulfate Aug 01, 2009 I've been on it for almost 3 years and my weight gain is due to me seeking comfort from the pain by eating too much sweets. Joy. Lupus, Fibromyalgia, Glaucoma, Asthma, Hypothyriodism, Sleep Apnea, Degenerative Disk and Facet Disease, and Allergies. When life throws you lemons. View detailed reports from patients taking hydroxychloroquine sulfate who experienced abnormal weight gain. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. I've been taking hydroxychloroquine since last Autumn - dose increased to 400 mg per day in April. I think it helps me, but it can take 6 months to kick in. Still have to be really careful not to get over-tired. Can give you wind and stomach bloating. My Lupus has been really quiet for about 2 yrs, and I'm afraid to change anything. The Plaquenil drug side effects list weight loss, but some people have reported weight gain instead. My rheumy wants me to come down and then off my Plaquenil, but I've been resisting simply because I'm afraid to. Side effects of hydroxychloroquine weight gain Hydroxychloroquine Side Effects Common, Severe, Long Term., Hydroxychloroquine Sulfate Abnormal Weight Gain Reports - DrugInformer Chloroquine mechanism of drug action and resistance in plasmodium falciparumAdverse effects of chloroquineManufacturers of plaquenil Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. How good is Hydroxychloroquine, and any side effe. - HealthUnlocked. Hydroxychloroquine Side Effects - GoodRx. If you go to or rxlist.com, neither of them list weight gain as a side effect, while they both list "nausea, vomiting, stomach pain; loss of appetite, weight loss" as side effects. During trials, if any adverse event read possible side effect occurs, and the company can't prove it wasn't the drug, it goes on the list as a side effect. The results of the present study demonstrate abnormal weight gain as a side effect of long-term treatment with doxycycline and hydroxychloroquine. Moreover, doxycycline and hydroxychloroquine treatment exhibits a reproducible effect on the community structure of the gastrointestinal microbiota in humans. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use.