One class of medications can lead to more severe vision loss in people with the wet form of the disease, and another class of drugs may have a beneficial effect. Fortunately, very few prescription drugs have any known detrimental effects for people with AMD. Plaquenil leaky gut Ms and plaquenil Does plaquenil treat inflammation The investigators think that there is a connection between the use of plaquenil and the prevention of Age related macular degeneration AMD. The investigators believe that the use of plaquenil makes bruch's membrane thicker, thereby preventing Chroidal Neovascularization CNV growth. Because the patient has previous macular pathology, should we make a recommendation to stop the Plaquenil? It’s an important question to address, because pre-existing macular pathology is a risk factor for the development of retinal toxicity according to the new screening recommendations. Hi this is my first post. I am on Plaquenil and have been only for 3-4 years now. I have noticed that my eyesight is getting worse. I went to my eye doctor 6 months ago and I was using cheater glasses at 150 strength and I complained about them not seeming strong enough which they weren't they should have been 200 strength. Doctors often put patients with certain potentially life-threatening cardiovascular conditions on this blood thinner. Warfarin (Coumadin®), which is an anticoagulant blood thinner, is one exception. Using plaquenil in end stage macular degeneration Age-related Macular Degeneration AMD The Four Stages of., Pause the Plaquenil? Amsler grid and hydroxychloroquine maculopathyQuit plaquenilPlaquenil generic brand Wet macular degeneration can result from progression of dry macular degeneration, left untreated, and affects about 10% of macular degeneration patients. If AMD is found first in one eye, the other eye follows the same progression. How to Reduce Your Risk of Blindness From Macular Degeneration. Has anyone experienced plaquenil toxicity with damage to eyes? -. Medication Cautions in Macular Degeneration - AMDF. Aug 29, 2014 Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus erythematosus SLE and other inflammatory and autoimmune diseases. Researchers suggest that one central point in both eyes indicates toxicity and one should have a low threshold with regards to any defects. 19 The misinterpreted visual field defect using the larger testing strategies could potentially delay the diagnosis of Plaquenil toxicity resulting in irreversible vision loss. Due to the possibility of. Nov 01, 2015 H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. The most common side effect associated with its use is retinal toxicity, which may be irreversible.