Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9. Hydroxychloroquine Sulfate is a potent inhibitor of autophagy. Patient teaching on hydroxychloroquine Chloroquine autophagy hela Test for plaquenil retinopathy History of plaquenil Name Hydroxychloroquine sulfate Drug Entry Hydroxychloroquine. Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. 2 Hydroxychloroquine is an aminoquinoline like chloroquine. 8 It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. 8. Please note that the molecular weight for this compound is batch-specific due to variable water content. Packaging Packaged under inert gas Warning Toxicity Harmful C Reconstitution Following reconstitution, aliquot and freeze -20°C. Stock solutions are stable for up to 3 months at -20°C. Hydroxychloroquine Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor TLR 7/9. HCQ treatment inhibits RCC (renal cell cancer) cell growth, promotes apoptosis, inhibits mitochondrial oxygen consumption, and increases rates of glycolysis In vitro kinase assays: with purified proteins, recombinant S6 protein and recombinant active P70S6K are incubated in 1x kinase buffer with various amount of HCQ or RAD001 in the presence (25 μM) or absence of ATP for 30 minutes at 30°C. It prevents lysosomal acidification, thereby interfering with a key step in the autophagic process. Hydroxychloroquine sulfate molecular weight Plaquenil - FDA prescribing information, side effects and uses, Hydroxychloroquine Sulfate - Calbiochem Sigma-Aldrich Plaquenil antibiotic interactionsTylenol plaquenilPlaquenil effects on eyes Hydroxychloroquine C18H26ClN3O CID 3652 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities. Hydroxychloroquine C18H26ClN3O - PubChem. Hydroxychloroquine Sulfate Autophagy inhibitor Read.. Hydroxychloroquine sulfate Supplier CAS 747-36-4 Tocris.. Hydroxychloroquine sulfate. is 2-4-7-Chloro-4-quinolyl aminopentyl ethylaminoethanol sulfate 11. Its structural formula is The molecular weight of hydroxychloroquine sulfate is 433.95, and molecular formula is. C. 18 H 26 ClN 3 O. H 2 SO 4. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate. May be stored at RT for short-term only. Long-term storage is recommended at 4°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Jul 08, 2019 The molecular weight of hydroxychloroquine sulfate is 433.95, and molecular formula is C 18 H 26 ClN 3 O. H 2 SO 4. Hydroxychloroquine Sulfate Tablets, USP contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration.