Please review the following URL and make sure that it is spelled correctly. Hi everybody, I was wondering if Plaquenil's primary mode of action was to suppress the immune system? Aralen drug interactions 200 20 000 chloroquine But you can’t even compare it to the only other things I have to treat lupus—prednisone, where 100 percent of people get side effects, or immunosuppressive drugs, which suppress the immune system, potentially causing infections, low blood counts, and liver toxicity. Lupus is an auto-immune disease in which the immune system cannot distinguish between threats like viruses and bacteria, and healthy cells and tissue. As a result, the body produces antibodies that inflict cell damage, most commonly targeting joints, skin, kidneys and the nervous system. Join the group and find support for coping with lupus. A recent large study of people with cardiovascular disease found that hydroxychloroquine Plaquenil does not increase the risk of infection and methotrexate increases the risk of infection only slightly. The concern with immune suppression is that the virus could replicate more freely and cause more severe or extensive disease, says Dr. Winthrop. 1 month ago and prior to taking it I rarely ever got sick with colds,flu etc. I am asking this question, because I started this med approx. Plaquenil and immune system Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Stopping plaquenil. DailyStrength Plaquenil and cataractsGreater mekong subregion chloroquine resistanceHydroxychloroquine 200 mg for lupusChloroquine 250 mg Re want to know good stuff about plaquenil Sorry to be a party pooper here, but I have been on Plaquenil for 5 months and can't say I feel any difference at all. If anything I am sleeping all day but for just about 1 1/2 hours at a time. Immune & Autoimmune - Lupus want to know good stuff about plaquenil. Coronavirus and Arthritis What You Need to Know Arthritis Foundation. Will you have Immune system disorder with Plaquenil - eHealthMe. RA is a systemic autoimmune disease in which the immune system attacks the joints and can affect other parts of the body.1 Several drugs to treat RA -- biologics Enbrel, Humira, etc. and DMARDS Plaquenil, methotrexate suppress the immune system.2 Suppressing the immune system helps slow or prevent damage to joints and other body systems. I have been taking Plaquenil hydroxychloroquine for about 10 months. Since August I’ve had some strange infections. First I got shingles. Then I started with a bacterial vaginosis. I discontinued the Plaquenil for about a week when I was diagnosed with shingles and I thought it may have helped it not be so bad. The bacterial vaginosis just won’t go away. I use metro gel and it’s goes. Plaquenil itself probably does not have a direct affect on your immune system - it is a DMARD and is not considered to be an immunosuppressant. However, many with active autoimmune diseases feel that they are not succeptible to many of the common viruses that they are exposed to - somewhat of a silver lining.