Its cause is not known, and most episodes of granuloma annulare clear up after a few years, with or without treatment. Although granuloma annulare can occur in people of any race and at any age, it is most commonly seen in children and young adults. How to make hydroxychloroquine at home Antiinflammatory plaquenil What is granuloma annulare? Granuloma annulare is a long-term chronic skin disease consisting of a rash with reddish bumps arranged in a circle or ring. There are also many types of Granuloma Annulare. They are classified based on the distribution and their symptoms. These types include Localized Granuloma Annulare – this type occurs on your elbows, knees, hands, and feet. Generalized Granuloma Annulare – this type is where the lesions are spread out your entire body. It is a severe case. Granuloma annulare GA is skin disorder that most often causes a rash with red bumps erythematous papules arranged in a circle or ring pattern annular. GA is not contagious and is not cancerous. The rash may be localized or generalized. The lesions of granuloma annulare are usually found in the same areas on both sides of the body (symmetrically). Females are slightly more likely than males to develop granuloma annulare. Chloroquin andgranuloma annulare Granuloma annulare - Symptoms, diagnosis and treatment BMJ., Granuloma Annulare - Pictures, Causes, Contagious, Symptoms, Treatment. Plaquenil law suits While there is limited evidence for their use in this indication, antimalarial agents e.g. hydroxychloroquine or chloroquine are the most widely supported and most often used first-line drugs. Grewal SK, Rubin C, Rosenbach M. Antimalarial therapy for granuloma annulare results of a retrospective analysis. Granuloma annulare - Treatment algorithm BMJ Best Practice. Granuloma annulare Genetic and Rare Diseases Information.. Granuloma annulare - Diagnosis and treatment - Mayo Clinic. In severe cases of generalized granuloma annulare, your doctor may recommend a special kind of ultraviolet light therapy called psoralen plus ultraviolet A PUVA. This treatment combines exposure to ultraviolet light phototherapy with drugs called psoralens, which help make your skin more receptive to the effects of ultraviolet light. There are other less common forms of granuloma annulare Generalised granuloma annulare 8-15% of cases. Adults are more commonly affected. It is characterised by widespread small bumps or discoloured patches of skin, with a tendency to present on the trunk. Subcutaneous granuloma annulare is rare. It is more commonly seen in children. Three cases are presented in which erythema annulare centrifugum developed as the result of treatment of chronic discoid lupus erythematosus with antimalarials. The possibility that the eruption represented a known variant of lupus erythematosus was excluded by its prompt regression on discontinuing.