I've been on it for 10 months and I noticed within a couple of weeks that I was pretty itchy. I recently went to the dermatologist for a rash and he said that my rash was from scratching. Hydroxychloroquine 400 mg Vitamin c and plaquenil 25 μm chloroquine diphosphate Does hydroxychloroquine cause cirrhosis Hi, I need some help please, I have been on Plaquenil actually hydroxychloroquine sulfate since May and have had great physical benefit with this drug. However for the past two weeks,I have had very uncomfortable itchy skin that radiates to different parts of my body. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. It can reduce skin. I have to tell you though that I was bad, I would scratch and scratch at them and caused an ugly rash and broke skin so your dermy is right. I think the itch has become worse since I started on Cymbalta. I had some itching in the beginning of taking Plaq mostly on my upper arms but it eventually went away. Hydroxychloroquine itchy skin Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Hydroxychloroquine Plaquenil Is hydroxychloroquine the same as plaquenil Plaquenil and Itching - from FDA reports Summary Itching is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have Pain. Will you have Itching with Plaquenil - eHealthMe. Hydroxychloroquine Oral Uses, Side Effects, Interactions, Pictures.. Hydroxychloroquine Oral Route Precautions - Mayo Clinic. Background Hydroxychloroquine sulfate and other antimalarial drugs have been used successfully as adjunctive therapy for patients with cutaneous lesions of dermatomyositis over the past 20 years. An increased incidence of cutaneous reactions to hydroxychloroquine has been postulated to occur. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, ringing in your ears, mood changes, nervousness, irritability, skin rash, itching, or; hair loss. I have had to stop my plaquenil and aside from the fatigue and joint pain that I knew I would have, I also now have a sunburned look on my face when I go out in the sun and itching skin, almost like a hive type rash on my back.