Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Who can do plaquenil eye exams Homocysteine plaquenil Plaquenil cheapest Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away. This medicine may cause hypoglycemia low blood sugar. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. I was taking hydroxychloroquine up until three days ago for RA treatment. I was unable to get in contact with my Rheumy. but after viewing the side effects in more dept I've stopped taking it. Hopefully, my dr. will call me back soon. hydroxychloroquine is the generic form of Plaquenil but the side effects are the same. My thigh muscles are so. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil side effects muscle weakness Hydroxychloroquine Plaquenil Side Effects & Dosage for., Plaquenil Side Effects Common, Severe, Long Term - Chloroquin functional groups What are some other side effects of Hydroxychloroquine? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away Dizziness. Headache. Feeling nervous and excitable. Hydroxychloroquine Indications, Side Effects, Warnings.. Hydroxychloroquine - thigh muscle weakness?. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Summary Weakness is found among people who take Hydroxychloroquine sulfate, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have Osteoporosis. Weakness is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Osteoporosis. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.