Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Hydroxychloroquine erg Plaquenil copay cards Abstract. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Eye Exam and Testing for Plaquenil. For the first 5 years annual screening is appropriate. In addition to the previous discussion of a thorough complete eye exam with best corrected vision, central visual field, color vision, and dilated retinal exam, other tests include multifocal ERG, spectral domain OCT, and autofluoresence of the macula. Common DMARDs include methotrexate Trexall, Otrexup, others, leflunomide Arava, hydroxychloroquine Plaquenil and sulfasalazine Azulfidine. Side effects vary but may include liver damage, bone marrow suppression and severe lung infections. Biologic agents. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil ff erg severe Despite Plaquenil dosing recommendations, retinal toxicity., Plaquenil Hydroxychloroquine Side Effects and Adverse Reactions Chloroquine phosphate reef2reef The electroretinogram ERG is the most direct and objective test available for evaluating the function of the retina. Electrodes are placed on the skin around the eye and a soft gold foil electrode is positioned over the lower lid to be in contact with the cornea through the tear film. Electroretinogram ERG Macula and Retina Institute. Rheumatoid arthritis - Diagnosis and treatment - Mayo Clinic. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Sep 15, 2014 Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Aug 06, 2014 Hydroxychloroquine, sold under the brand name Plaquenil Sanofi-Aventis, is an antimalarial drug that has gained widespread use in treating various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis. 1 By some estimates, more than 150,000 patients are on long-term therapy with this medication in America alone. 2 Retinal toxicity associated with HCQ use is. Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.