Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Rheumatoid arthritis chloroquine Plaquenil when l medication Plaquenil newborn It does not appear to be safe during pregnancy. Hydroxychloroquine is in the antimalarial and 4-aminoquinoline families of medication. Hydroxychloroquine was approved for medical use in the United States in 1955. Hydroxychloroquine Plaquenil and prednisone are considered safe during pregnancy. Methotrexate and cyclophosphamide Cytoxan should not be used in pregnancy and should be discontinued for at least a month prior to getting pregnant. Ask your doctor to help you weigh the benefits and risks all your medications. In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. This is called her background risk. This sheet talks about whether exposure to hydroxychloroquine may increase the risk for birth defects over that background risk. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Is hydroxychloroquine safe during pregnancy Hydroxychloroquine Use During Pregnancy, Lupus and Pregnancy Tips for Living with Lupus While Pregnant Pill plaquenil generic dog bone shappedSide effects of malaria pills chloroquineHydroxychloroquine sulfate side effects rheumatoid arthritisDoes plaquenil deplete vitamin d May 13, 2009 Other studies have reported that HCQ is safe to use during pregnancy but had no control group 35-40. All 4 of the studies 27 - 30 assessed the presence of congenital defects in babies born to women with autoimmune diseases Additional file 1, Table S2 and Figure Figure2a. 2a. Systematic review of hydroxychloroquine use in pregnant.. Hydroxychloroquine MotherToBaby. Hydroxychloroquine Plaquenil RheumTutor. In animal studies on Plaquenil hydroxychloroquine and pregnancy, the medication crossed the placenta and accumulated in the eyes of the fetus when it was given to pregnant animals. Although human studies are lacking, available evidence suggests a relatively low risk to the fetus. Of these, 118 women used the DMARD during their pregnancy or while breastfeeding, with 149 children exposed to hydroxychloroquine during the neonatal or postnatal periods. The majority of women n = 76 used the drug during pregnancy and breastfeeding, 42 during pregnancy only, and 4 only while they were breastfeeding. CONCLUSION HCQ continuation is probably safe during pregnancy in patients with lupus, but there is no obvious advantage in commencing treatment.