It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Hydroxychloroquine step 1 Plaquenil and radiotherapy Hydroxychloroquine clinical trial cancer Plaquenil skutki uboczne People with kidney and liver problems have a tougher time eliminating the drug from their system so they are at higher risk because the body is going to retain more of the drug for a longer period of time. The recommendation is to have a baseline eye exam with dilation and a visual field test before or soon after starting the drug. Core tip The existence of liver disease associated with lupus itself, or increased susceptibility to concomitant liver diseases, either autoimmune or non-autoimmune ones, is still somewhat controversial, and difficult to diagnose. Data in the literature are scarce, and often based on case reports or clinical studies with limited patient size or histological evidence. Acute kidney failure is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years, also take medication Enbrel, and have Osteoporosis This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Plaquenil and liver problems Common and Rare Side Effects for Plaquenil Oral, Challenge of liver disease in systemic lupus erythematosus. Plaquenil 200 mg during pregnancy Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria. Plaquenil Side Effects on Your Eyes and Vision. Will you have Acute kidney failure with Plaquenil - eHealthMe. Long-Term Side Effects of Plaquenil for Rheumatoid.. Yes, plaquenil can affect your liver. My doctor runs blood work at 6 month intervals to check on liver. I also get 6 month eye exams while on plaquenil. Plaquenil can cause serious liver or heart problems, especially if you use certain medicines at the same time, including other medicines to treat malaria; an antibiotic or antifungal medicine; antiviral medicine to treat hepatitis or HIV/AIDS; antidepressants or antipsychotic medicines; birth. Plaquenil belongs in a class of medications known as disease-modifying antirheumatic drugs DMARDs. It is most often prescribed to patients who try and fail biologic DMARDs biologic DMARDs, also known as biologics, are medications made up of living matter such as human cells, bacteria and yeast, cannot tolerate biologics, or for those who fear trying the newer biologic DMARDs.