Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Chloroquine phosphate saltwater Chloroquine molecular formula The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1. It succinctly makes the case for screening, and Mar 08, 2017 A new version of the AAO’s recommendations came out in March 2016. The Committee on Rheumatologic Care of the American College of Rheumatology ACR has regularly updated the ACR’s position statement on screening for HCQ retinopathy and appropriate dosages, with the most recent version out in August 2016. The AAO published dosing and screening recommendations for chloroquine and hydroxychloroquine in 2016, revising previous recommendations published in 2011. The current maximum daily HCQ dose. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Aao 2016 plaquenil Hydroxychloroquine usage in US patients, their experiences of., Hydroxychloroquine dosage recommendations often ignored. Plaquenil treatment sjogren& 39Plaquenil and acid refuxPlaquenil boilsHow to take aralen Problems with Plaquenil Use Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. New Plaquenil Guidelines -. Despite Plaquenil dosing recommendations, retinal toxicity.. The 2016 American Academy of Ophthalmology.. Twenty-seven percent of cases of hydroxychloroquine retinopathy in obese women had ostensibly safe dosing based on 2016 AAO guidelines. Overdosing of obese women by 2016 AAO guidelines is not rare. Daily dosing based on the older 6.5-mg/kg ideal weight threshold is safer in women with a body mass index of 30 kg/m 2 or more. New Perspectives in Rheumatology Avoiding Antimalarial Toxicity. Adoption of the 2016 recommendations from the AAO will make bull's eye maculopathy an esoteric question on a board examination rather than a frightening, overlooked clinical phenomenon. Recommendations on screening for chloroquine and hydroxychloroquine retinopathy 2016. Screening for chloroquine and hydroxychloroquine retinopathy. Ophthalmology. 92 2011;1182415-22. 93 5. Marmor MF, Kellner U, Lai TY, Melles RB, Mieler WF, American Academy of O. 94 Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy 2016 95 Revision. Ophthalmology. 2016. 96 6.