Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Toxicity of hydroxychloroquine Typical plaquenil dosage Is plaquenil a mitochondrial toxin Hydroxychloroquine and breastfeeding Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. I would be hesitant to stop the Plaquenil, as from what I read, it doesn't seem to have side effects like this. Also doctors get somewhat irate if you keep starting and stopping meds, without consulting them about it. RARE side effects If experienced, these tend to have a Severe expression A Disease With Shrinking And Weaker Muscles Called Myopathy A Disorder Of The Peripheral Nerves That Enable Movement Called. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Side effects coming off plaquenil Plaquenil Side Effects Common, Severe, Long Term -, Coming Off Plaquenil questions - Sclero Forums MAIN. Is it safe to take gabapentin and plaquenilChloroquine side effects medscapePlaquenil herx symptomsPlaquenil safe during pregnancyLysosomotropic agent chloroquine which Summary Withdrawal syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Lyrica, and have Fibromyalgia. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA. Will you have Withdrawal syndrome with Plaquenil - eHealthMe. Common and Rare Side Effects for Plaquenil Oral. Let me tell you what weaning down from Plaquenil is like.. Unfortunately, it's not a good idea to stop methotrexate "cold turkey.". Some people experience no side effects to suddenly stopping taking this medication, but it does have the potential for creating an intense RA flare. The goal of medication is to protect your joints and other systems in the body internal organs, such as the heart. Some patients decide to stop taking statins, a cholesterol-lowering drug, if they experience side effects. A new study tracked how they did. Nov 12, 2009 Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up.