It is multifocal and small areas may merge to form larger irregular areas. Symptoms are often absent, but they may include: folliculitis. Hydroxychloroquine pediatric dose Plaquenil and lexapro interactions Hydroxychloroquine sulfate 200 mg patient information leaflet Lichen planopilaris LPP is an inflammatory condition that causes patchy hair loss, mainly on the is a form of lichen planus that most often affects women in young adulthood. There are 3 forms of LPP, distinguished by specific patterns and locations of symptoms classic LPP, frontal fibrosing alopecia, and Lassueur Graham-Little Piccardi syndrome. Feb 27, 2018 Besides this comparative analysis, there are other studies on the use of antimalarials in LPP.1,2,9–14 In particular, a prospective study on 12 patients treated with hydroxychloroquine 400 mg daily for 6 months found a good response in three cases although their hair count was in a decreasing number and progression in eight instances; one. In 2010 Chiang et al. introduced the LPPAI to analyse pre- and post-treatment response with hydroxychloroquine in 40 patients with LPP, including 11 with FFA. The data showed a statistically significant reduction in LPPAI scores at 6 months with continued significant reduction in LPPAI scores at 12 months. Data indicate that hydroxychloroquine. Biopsy from an already scarred area of hair loss is unhelpful. However, it is not always possible to make a diagnosis on biopsy. Hydroxychloroquine for lpp Treatment Options for Lichen Planopilaris What to consider., Therapeutic management of classic lichen planopilaris a. Chloroquine itchChloroquine nurses responsibility Efficacy of hydroxychloroquine use after six and 12 months of treatment, whereas Assouly et al. reported little success following six months of hydroxychloroquine therapy in 12 patients.4,8 Antimetabolite therapy with mycophenolate mofetil has been shown to be effective in the treatment of LPP.9 Cho et al. showed that six Lichen Planopilaris A Case Report and Therapeutic Management.. Frontal Fibrosing Alopecia The Trichological Society. Lichen planus - Diagnosis and treatment - Mayo Clinic. Lichen planopilaris LPP is a cell-mediated scarring alopecia that causes inflammation of the scalp and the eventual destruction of hair follicles in affected areas. Current literature on treatment of LPP remains limited with no definitive treatment approach being recognized, although a combination of topical/intralesional steroids and orally administered hydroxychloroquine remains the most. We also introduce the LPP Activity Index LPPAI, which allows numeric scoring of the symptoms, signs, activity, and spreading of the condition for statistical comparison. Using the LPPAI, we show that treatment with hydroxychloroquine resulted in statistically significant improvement. Lichen planopilaris I see patients with LPP every 6 months after their transplant for the first 2 years. If there is any sign of the disease coming back, we restart clobetasol and sometimes oral medications like hydroxychloroquine. Other options for cosmetic improvement of LPP besides hair transplants include use of a wig, hairpiece.