It’s also referred to as knee instability or weak knees. While it’s often accompanied by pain, this isn’t always the case. Plaquenil bull's eye maculopathy Plaquenil and cyclosporine Expired chloroquine Thank you so much. I think that this information and possibly a write up about this should be posted on the site. I’m sure I’m not the only person with RA inquiring about this. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells anemia. Apr 10, 2019 Plaquenil is sometimes given only once per week. Choose the same day each week to take this medicine if you are on a weekly dosing schedule. Take Plaquenil with a meal or a glass of milk. To prevent malaria Start taking Plaquenil 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay. However, if it keeps happening, it could be a sign of something else. If it’s only happened once or twice, you may have just stumbled. Plaquenil knee weakness Plaquenil Side Effects Common, Severe, Long Term -, Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Eye problems on hydroxychloroquineChloroquine primaquine babesia forumPlaquenil exfoliative dermatitisZydus hydroxychloroquine gluten free Plaquenil and Knee joint replacement by duration, gender and age - a study of FDA data Summary Knee joint replacement is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 10+ years, also take medication Enbrel, and have Pain. Plaquenil and Knee joint replacement by duration, gender.. Plaquenil Uses, Dosage & Side Effects -. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Nov 28, 2010 Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells these are messengers for your immune system, if you will from interacting with your T-Cells a special type of white blood cell which through a convoluted and boring process, causes inflammation. Muscle weakness can be a symptom of many chronic conditions and acute infections. It can also be a side effect of certain medications. Find out more about the causes of muscle weakness here. Jul 18, 2008 I have been on 400 mg daily of Plaquenil, last week my doctor took me off of it ue to increase in the pain I had been having in lower back and unbelievable pain in my left leg and especially the extreme pain in the heel of my left foot. It was becoming painful to walk. After 5 days of stopping pain was 80% better.