Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil lowers blood sugar Hydroxychloroquine gh Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. I was wondering if anyone experienced blurry vision on Plaquenil. I have been on Plaquenil for about a month. Every now and then I notice some of the words on the television are blurry, then there are other times my eyes are fine. Should this be a big concern? I Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. A Disorder Of The Retina Of The Eye; Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and eyesight Eye screening for patients taking hydroxychloroquine Plaquenil, Plaquenil eye problems Mayo Clinic Connect Chloroquine proguanil combination Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Common and Rare Side Effects for Plaquenil Oral. Study Finds Blood Levels of Plaquenil may be Important.. I'm on Plaquenil, and after the first week's GI upset, I have had no problems with it. Did you take yourself off Plaquenil, or did your doctor tell you to go off it? And as far as the vision issue goes, toxicity causing vision loss is very rare if you are on the right dose for your height and if you get regular eye exams. Aug 29, 2014 In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias joint pain, dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” Newer guidelines state that daily dose 5mg/kg of real weight/day can lead to toxicity. Retinal toxicity is irreversible and can progress after cessation of hydroxychloroquine, thus early screening is important to limit potential vision loss. Baseline screening and annual screening after five years is recommended.